Gene description for SF3B1 |
Gene name |
splicing factor 3b subunit 1 |
Gene symbol |
SF3B1 |
Other names/aliases |
Hsh155 MDS PRP10 PRPF10 SAP155 SF3b155 |
Species |
Homo sapiens |
Experiment description of studies that identified SF3B1 in Glioblastoma cells |
1
|
Experiment ID | 203 |
Identified molecule | mrna
|
Extracellular vesicle type | Microvesicles |
MISEV | EVs |
Identification method | Microarray
|
PubMed ID |
19011622
|
Organism | Homo sapiens |
Experiment description | Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers |
Authors | Skog J, Wüer T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO |
Journal name |
Nat Cell Biol
|
Publication year | 2008 |
Sample | Glioblastoma cells |
Sample name | Glioblastoma cells |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Filtration |
Flotation density | - |
Molecules identified in the study | Protein miRNA mRNA |
Methods used in the study | RT-PCR Antibody array Microarray |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 1243 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
25261722
|
Organism | Homo sapiens |
Experiment description | Inflammatory cytokines, interleukin-1 beta and tumor necrosis factor-alpha, upregulated in glioblastoma multiforme, raise the levels of CRYAB in exosomes secreted by U373 glioma cells. |
Authors | Kore RA, Abraham EC. |
Journal name |
Biochem Biophys Res Commun.
|
Publication year | 2014 |
Sample | Glioblastoma cells |
Sample name | U373 cells treated with 10ng/ml of TNF-. |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV140183: EV-METRIC:22%
|
|
|
3
|
Experiment ID | 1070 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
29937354
|
Organism | Homo sapiens |
Experiment description | Apoptotic Cell-Derived Extracellular Vesicles Promote Malignancy of Glioblastoma Via Intercellular Transfer of Splicing Factors. |
Authors | Pavlyukov MS, Yu H, Bastola S, Minata M, Shender VO, Lee Y, Zhang S, Wang J, Komarova S, Wang J, Yamaguchi S, Alsheikh HA, Shi J, Chen D, Mohyeldin A, Kim SH, Shin YJ, Anufrieva K, Evtushenko EG, Antipova NV, Arapidi GP, Govorun V, Pestov NB, Shakhparonov MI, Lee LJ, Nam DH, Nakano I. |
Journal name |
Cancer Cell
|
Publication year | 2018 |
Sample | Glioblastoma cells |
Sample name | Untreated GBM157 - Exo - Biorep2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
-
|
|
|